Our Pre-formulation R&D team leverages cutting-edge technologies to lay a solid scientific foundation for successful drug product development. Using predictive modelling, high-throughput screening, and state-of-the-art analytical tools, we assess the physicochemical, biopharmaceutical, and mechanical properties of APIs with precision and speed.
Pre-Formulation Services
Solid-State Characterization
By integrating tools like X-ray powder diffraction (XRPD),differential scanning calorimetry (DSC), Thermogravimetric Analysis (TGA) , particle size analysis, and in silico simulations, we identify optimal formulation strategies early in the development cycle—minimizing risk, reducing timelines, and ensuring robust downstream performance.
pH solubility and stability studies
In pH solubility study and stability studies, we examine the behaviour of the drug substance in different pH conditions to optimize its in-vivo performance in drug product.
From solubility enhancement to polymorph screening and compatibility studies, our data-driven approach accelerates the formulation journey while maintaining a sharp focus on quality, scalability, and regulatory readiness.
Screening and Selection of Salt
The salt form isn't just a formulation detail—it's a strategic decision that can influence every stage of a drug's lifecycle, from lab bench to pharmacy shelf. Our expert team capable of screening and characterization to identify the right salt form of API
Drug Excipient Compatibility Study
We conduct drug-excipient compatibility study is to evaluate whether the active pharmaceutical ingredient (API) interacts negatively with any of the excipients in the formulation. The goal is to ensure stability, safety, and efficacy of the final product.
Particle size and Particle morphology study
We utilize Laser diffraction technology, Malvern mastersizer, Scanning Electron Microscopy(SEM), Optical microscopy to assess the size, shape, particle size distribution of drug particle, which is directly impact on drug’s performance, manufacturability, and stability.